Inj should always be made slowly w/ frequent aspirations. Reports of chondrolysis. Should not be used for post-op intra-articular continuous infusion. Epidural or spinal haematoma. Debilitated, elderly or acutely ill patients. Patients w/ epilepsy, impaired cardiac conduction, bradycardia, severe shock or digitalis intoxication; impaired CV function; preexisting abnormal neurological pathology eg, myasthenia gravis. Serious diseases of the CNS or of the spinal cord eg, meningitis, spinal fluid block, cranial or spinal haemorrhage, tumours, poliomyelitis, syphilis, tuberculosis or metastatic lesions of the spinal cord. Hepatic &/or renal impairment, genetic predisposition to malignant hyperthermia. Paracervical blocks during pregnancy. Porphyric patients. Avoid intravascular inj. May temporarily impair locomotion & coordination.
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